Difficult to Express Proteins 2014
May 5 - 6, 2014
Boston MA , USA
Cambridge Healthtech Institute’s Ninth Annual
Difficult to Express Proteins
Harnessing Innovation to Improve Expression and Function
Part of the Tenth Annual PEGS: the essential protein engineering summit
May 5-6, 2014 | Seaport World Trade Center | Boston, MA
Membrane proteins, ion channels, toxic or insoluble proteins, low abundance protein complexes, vaccines and other “finicky” proteins often are the best choices for therapeutics, yet their successful expression is a minefield of failures and challenges. This conference will present innovative and imaginative methods to make those difficult to express proteins more “expressible” and functional.
Topics will include, but are not limited to:
Novel host, vector, transfection and cloning strategies
Solving problems in recombinant protein expression
Cell-free methods for finicky proteins
Controlling disulfide bonds
Folding, refolding and function
Improving expression of extra-cellular proteins
Rational vector design and pathway modulation to facilitate expression of difficult proteins
Utilizing transient gene expression
Achieving proper glycosylation, pegylation, sialylation, etc.
Expression of protein complexes and toxic proteins
Overcoming ion channel expression problems
Difficult to Express Proteins
Harnessing Innovation to Improve Expression and Function
Part of the Tenth Annual PEGS: the essential protein engineering summit
May 5-6, 2014 | Seaport World Trade Center | Boston, MA
Membrane proteins, ion channels, toxic or insoluble proteins, low abundance protein complexes, vaccines and other “finicky” proteins often are the best choices for therapeutics, yet their successful expression is a minefield of failures and challenges. This conference will present innovative and imaginative methods to make those difficult to express proteins more “expressible” and functional.
Topics will include, but are not limited to:
Novel host, vector, transfection and cloning strategies
Solving problems in recombinant protein expression
Cell-free methods for finicky proteins
Controlling disulfide bonds
Folding, refolding and function
Improving expression of extra-cellular proteins
Rational vector design and pathway modulation to facilitate expression of difficult proteins
Utilizing transient gene expression
Achieving proper glycosylation, pegylation, sialylation, etc.
Expression of protein complexes and toxic proteins
Overcoming ion channel expression problems
Venue
Location: Seaport World Trade Center Boston
The Boston World Trade Center is a part of a non-profit organization which promotes the growth of World Trade Centers by developing international business relationships through a cooperative exchange..
617.385.4212
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