National Symposium cum Workshop on “Recent Trends in Structural Bioinformatics and Computer 2010

ALAGAPPA UNIVERSITY
Accredited with “A” grade by NAAC)
KARAIKUDI-630 003, TAMIL NADU, INDIA

DEPARTMENT OF BIOINFORMATICS,In Association with Schrödinger, USA
Organizing
3rd National Symposium cum Workshop on “Recent Trends in Structural Bioinformatics and Computer Aided Drug Design” [SBCADD’2010]
December 20th - 22nd, 2010

THEME OF THE SYMPOSIUM AND WORKSHOP
Structural Bioinformatics and in silico drug discovery methods reduce both time and cost of development of novel drug/lead molecules. Knowledge about the molecule, its interaction with the drug, molecular modeling, and new drug development creates an awareness of the molecule at the organ level and also aids in the prevention, diagnosis, and treatment of diseases. Computational tools have the advantage of delivering new lead candidates more quickly and at lower cost. In the 21st century, Drug discovery is expected to be different in two distinct ways: development of individualized medicines synthesized from genomic information and extensive use of in silico methods to facilitate target identification, structure prediction and lead/drug discovery. The computational methods expect more reliable and expeditious protocols for development of novel ideas, which increase the potential leads. The computer-assisted molecular design has succeeded in the QSAR and protein modeling algorithms to improve activity of lead compounds. Selecting candidates via the described in silico virtual screening, should help to reduce the list of candidate molecules and thereby reduce time and costs significantly. X-ray crystallography is the ultimate method to determine the 3-dimensional structures of biologically large and small molecules at atomic resolution. Crystallographic studies also provide unambiguous, accurate, and reliable 3-dimensional structural parameters, which are prerequisites for rational drug design and structure- based f