Nuclear Receptors Conference, Fusion Conferences, Cancun Mexico, 2018

Nuclear Receptors are, physiologically and pharmacologically, a critical superfamily of transcription factors. They drive key processes at every stage from development and reproduction to ageing and cancer. They are critical determinants of everyday health via their roles in metabolism and circadian rhythms. Nuclear receptors allow external factors to influence cellular pathways and the fact that many bind and are activated by small molecules means they represent highly druggable targets; currently, 13% of FDA-approved drugs target nuclear receptors. This meeting will address the new roles and novel crosstalk mechanisms that are emerging for many of the 48 human nuclear receptors, in health and disease. Key Sessions include: Further emerging roles for nuclear receptors in cancer Structural insights into nuclear receptor function and crosstalk Nuclear receptors’ role in epigenetic regulation and non coding RNA Nuclear receptors and DNA damage Nuclear receptors and cell cycle Nuclear receptors in metabolism/metabolic disease Nuclear receptors in the CNS For sponsorship opportunities contact Fusion Conferences. Please note registration fees include fixed accommodation (27, 28 Feb and 01 Mar 2018), an all-inclusive food and beverage package and conference attendance